Sucrose polyester does not inhibit gastric acid secretion or stimulate cholecystokinin release in men

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Sucrose polyester does not inhibit gastric acid secretion or stimulate cholecystokinin release in men.

Replacement of dietary fat by sucrose polyester reduces fat intake. However, little is known about the effects of sucrose polyester on gastrointestinal function. To investigate the effect on gastric acid secretion and on release of cholecystokinin into plasma, we perfused eight healthy male volunteers intraduodenally with sucrose polyester, digestible fat, or saline on separate days in random o...

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Sucrose polyester does not inhibit gastric acid secretion or stimulate cholecystokinin release in men1-3

Replacement of dietary lilt by sucrose polyester reduces fat intake. However, little is known about the effccts of sucrose polyester on gastrointestinal function. To investigate the effect on gastric acid secretion and on release of cholecystokinin into plasma, we perfused eight healthy male volunteers intraduodenally with sucrose polyester, digestible fat, or saline on separate days in random ...

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Cholecystokinin in the control of gastric acid secretion in humans.

This study was designed to determine the involvement of cholecystokinin (CCK) in the control of gastric acid secretion in men using loxiglumide, a specific CCK-receptor antagonist. Two groups of healthy subjects (A and B) were used: group A for studies of postprandial gastric secretion and group B for studies with exogenous gastric secretagogues. The cephalic phase activated by modified sham fe...

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Gastric inhibitory polypeptide does not inhibit gastric emptying in humans.

The insulinotropic gut hormone gastric inhibitory polypeptide (GIP) has been demonstrated to inhibit gastric acid secretion and was proposed to possess "enterogastrone" activity. GIP effects on gastric emptying have not yet been studied. Fifteen healthy male volunteers (23.9 +/- 3.3 yr, body mass index 23.7 +/- 2.3 kg/m(2)) were studied with the intravenous infusion of GIP (2 pmol.kg(-1).min(-1...

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How does cholecystokinin stimulate exocrine pancreatic secretion? From birds, rodents, to man

The field of cholecystokinin (CCK) stimulation of exocrine pancreatic secretion has experienced major changes in the recent past. This review attempts to summarize the current status of the field. CCK production in the intestinal I cells, the molecular forms of CCK produced and subsequently circulated in the blood, the presence or absence of CCK receptors on the isolated pancreatic acinar cells...

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ژورنال

عنوان ژورنال: The American Journal of Clinical Nutrition

سال: 1997

ISSN: 0002-9165,1938-3207

DOI: 10.1093/ajcn/65.3.761